Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine) – Side Effects, Interactions, Uses, Dosage, Warnings

Pneumococcal disease is a serious infection caused by a bacteria that can infect the sinuses, inner ear, lungs, blood, and brain. These conditions can be fatal.

Pneumococcal 15-valent conjugate vaccine is used in adults to help prevent disease caused by pneumococcal bacteria. This vaccine contains 15 different types of pneumococcal bacteria.

This vaccine helps your body develop immunity to the disease, but will not treat an active infection you already have.

Like any vaccine, pneumococcal 15-valent conjugate vaccine may not provide protection from disease in every person.


What is Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine) used for?

  • Pneumococcal Disease Prophylaxis


What is the most important information I should know about Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine)?

You should not receive this vaccine if you ever had a severe allergic reaction to a pneumococcal or diphtheria toxoid vaccine.

Tell the vaccination provider if you have:

  • heart problems;
  • a breathing disorder;
  • a weak immune system (caused by disease or by using certain medicine); or
  • if you are receiving radiation or chemotherapy.

You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.

Tell the vaccination provider if you are pregnant or breastfeeding.

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Side Effects

What are the side effects of Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Keep track of all side effects you have. If you ever need another pneumococcal 15-valent conjugate vaccine, you will need to tell the vaccination provider if the previous shot caused any side effects.

Becoming infected with pneumococcal disease is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is low.

Common side effects may include:

  • pain, swelling, or redness where a shot was given;
  • muscle or joint pain;
  • headache; or
  • feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

Pregnancy & Breastfeeding

Can I take Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine) if I’m pregnant or breastfeeding?

Tell the vaccination provider if you are pregnant or breastfeeding.


What drugs and food should I avoid while taking Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to take Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine)?

Use Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

This vaccine is given as an injection (shot) into a muscle.

Pneumococcal 15-valent conjugate vaccine is usually given as 1 shot.

What should I do if I missed a dose of Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine)?

Pneumococcal 15-valent conjugate vaccine is used as a single dose and does not have a booster schedule.

Overdose Signs

What happens if I overdose on Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine)?

An overdose of this vaccine is unlikely to occur.

If you think you or someone else may have overdosed on: Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Vaxneuvance (Pneumococcal 15-Valent Conjugate Vaccine), call 911


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