Tricitrates (Citric Acid K Citrate Na Citrate) – Side Effects, Interactions, Uses, Dosage, Warnings

Citric acid, potassium citrate, and sodium citrate is a combination medicine that helps make your urine less acidic. Sometimes called a urinary alkalizer, this medicine is used to treat acidosis or to prevent gout or kidney stones.

Citric acid, potassium citrate, and sodium citrate may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Tricitrates (Citric Acid K Citrate Na Citrate)?

You should not use this medicine if you have:

  • severe kidney disease;
  • decreased urination;
  • severe heart damage (such as from a prior heart attack);
  • untreated Addison's disease (an adrenal gland disorder); or
  • if you are on a low-salt diet or a low-potassium diet.

Tell your doctor if you have ever had:

  • kidney problems;
  • heart problems, high blood pressure;
  • toxemia of pregnancy;
  • swelling in your hands or feet, or in your lungs (pulmonary edema); or
  • an electrolyte imbalance (such as low levels of potassium or calcium in your blood).

Tell your doctor if you are pregnant or breastfeeding.

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Side Effects

What are the side effects of Tricitrates (Citric Acid K Citrate Na Citrate)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • swelling or severe pain in your stomach;
  • vomiting;
  • black or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
  • high potassium level–nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects may include:

  • nausea, vomiting; or
  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Tricitrates (Citric Acid K Citrate Na Citrate) if I’m pregnant or breastfeeding?

Risk cannot be ruled out
Based on FDA pregnancy categories

Tell your doctor if you are pregnant or breastfeeding.


What drugs and food should I avoid while taking Tricitrates (Citric Acid K Citrate Na Citrate)?

Ask your doctor before using an antacid, and use only the type your doctor recommends. Antacids that contain aluminum can interact with this medicine and cause serious side effects.

Avoid using potassium supplements or salt substitutes without your doctor's advice.

Dosage Guidelines & Tips

How to take Tricitrates (Citric Acid K Citrate Na Citrate)?

Use Tricitrates (Citric Acid K Citrate Na Citrate) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

This medicine is usually taken after meals and at bedtime. Follow your doctor's dosing instructions very carefully.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Mix the medicine with at least 4 ounces of water or juice. Stir and drink this mixture right away. Add a little more water to the glass, swirl gently and drink right away.

Drink plenty of liquids while you are taking this medicine.

You may need to follow a special diet. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.

You will need frequent blood and urine tests.

Store in a tightly-closed container at room temperature, away from moisture, heat, and freezing.

What should I do if I missed a dose of Tricitrates (Citric Acid K Citrate Na Citrate)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Tricitrates (Citric Acid K Citrate Na Citrate)?

Overdose symptoms may include diarrhea, vomiting, unusual thoughts, or a seizure.

If you think you or someone else may have overdosed on: Tricitrates (Citric Acid K Citrate Na Citrate),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Tricitrates (Citric Acid K Citrate Na Citrate), call 911


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