Tigan (Trimethobenzamide (Oral/Injection)) – Side Effects, Interactions, Uses, Dosage, Warnings

Trimethobenzamide is used to treat nausea and vomiting related to surgery or caused by stomach flu.

Trimethobenzamide may also be used for purposes not listed in this medication guide.


What is Tigan (Trimethobenzamide (Oral/Injection)) used for?

  • Nausea/Vomiting


What is the most important information I should know about Tigan (Trimethobenzamide (Oral/Injection))?

You should not use trimethobenzamide if you are allergic to it.

Tell your doctor if you have ever had:

  • liver disease; or
  • kidney disease.

Do not give this medication to a child or teenager without medical advice, especially if the child has a fever, flu symptoms, or chicken pox.

It is not known whether trimethobenzamide will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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Side Effects

What are the side effects of Tigan (Trimethobenzamide (Oral/Injection))?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking trimethobenzamide and call your doctor at once if you have:

  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
  • trouble speaking or swallowing;
  • problems with thought or memory;
  • pain, stiffness, or unusual muscle spasm in your neck;
  • tremors, feeling restless or being unable to sit still;
  • jaundice (yellowing of the skin or eyes);
  • a seizure (convulsions); or
  • low blood cell counts–fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Serious side effects may be more likely in older adults.

Common side effects may include:

  • headache, muscle cramps;
  • dizziness, drowsiness;
  • confusion, depressed mood;
  • blurred vision;
  • diarrhea; or
  • pain, stinging, burning, redness, or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Tigan (Trimethobenzamide (Oral/Injection)) if I’m pregnant or breastfeeding?

It is not known whether trimethobenzamide will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.


What drugs and food should I avoid while taking Tigan (Trimethobenzamide (Oral/Injection))?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can cause side effects.

Do not share this medicine with another person, even if they have the same symptoms you have.

Dosage Guidelines & Tips

How to take Tigan (Trimethobenzamide (Oral/Injection))?

Use Tigan (Trimethobenzamide (Oral/Injection)) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Trimethobenzamide is usually taken 3 or 4 times per day. Follow your doctor's dosing instructions very carefully.

Trimethobenzamide oral is taken by mouth. Trimethobenzamide injection is injected into a muscle by a healthcare provider.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose of Tigan (Trimethobenzamide (Oral/Injection))?

Since trimethobenzamide is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Tigan (Trimethobenzamide (Oral/Injection))?

If you think you or someone else may have overdosed on: Tigan (Trimethobenzamide (Oral/Injection)),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Tigan (Trimethobenzamide (Oral/Injection)), call 911



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