Capmatinib is used to treat non-small cell lung cancer that has spread to other parts of the body (metastatic) or cannot be removed with surgery.
Capmatinib is used only if your cancer has a specific genetic marker (an abnormal "MET" gene). Your doctor will test you for this gene.
Capmatinib may also be used for purposes not listed in this medication guide.
uses
What is Tabrecta (Capmatinib) used for?
- Non-Small Cell Lung Cancer
warnings
What is the most important information I should know about Tabrecta (Capmatinib)?
Tell your doctor if you have ever had:
- lung problems other than lung cancer; or
- liver disease.
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using this medicine should use effective birth control to prevent pregnancy. Capmatinib can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using capmatinib.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
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Side Effects
What are the side effects of Tabrecta (Capmatinib)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- new or worsening cough, chest pain, trouble breathing;
- fever, cough with mucus;
- severe ongoing nausea and vomiting; or
- signs of liver or pancreas problems–loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes).
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- trouble breathing;
- nausea, vomiting, decreased appetite;
- feeling weak or tired;
- abnormal liver function tests; or
- swelling in your hands or feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Tabrecta (Capmatinib) if I’m pregnant or breastfeeding?
You may need to have a negative pregnancy test before starting this treatment.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Interactions
What drugs and food should I avoid while taking Tabrecta (Capmatinib)?
Capmatinib could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Dosage Guidelines & Tips
How to take Tabrecta (Capmatinib)?
Use Tabrecta (Capmatinib) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take capmatinib with or without food.
You will need frequent blood tests to check your liver function.
Do not change your dose or stop taking this medicine without your doctor's advice.
Swallow the tablet whole and do not crush, chew, or break it.
If you vomit shortly after taking capmatinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
Throw away any tablets that are left 6 weeks after you first opened the bottle.
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
Overdose Signs
What happens if I overdose on Tabrecta (Capmatinib)?
(800) 222-1222
911
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