Serevent Diskus (Salmeterol Inhalation) – Side Effects, Interactions, Uses, Dosage, Warnings

Salmeterol inhalation is a bronchodilator that is used to prevent asthma attacks or exercise-induced bronchospasm.

Salmeterol inhalation is also used to treat chronic obstructive pulmonary disease (COPD) including emphysema and chronic bronchitis.

Salmeterol inhalation may also be used for purposes not listed in this medication guide.


What is Serevent Diskus (Salmeterol Inhalation) used for?

  • Asthma — Maintenance
  • Bronchospasm Prophylaxis
  • Chronic Obstructive Pulmonary Disease — Maintenance


What is the most important information I should know about Serevent Diskus (Salmeterol Inhalation)?

You should not use this medicine if you are allergic to salmeterol or to milk proteins.

Tell your doctor if you have ever had:

  • a food or drug allergy;
  • heart disease or high blood pressure;
  • epilepsy or other seizure disorder;
  • diabetes;
  • a thyroid disorder; or
  • liver disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Salmeterol can increase the risk of asthma-related hospitalization in children and teenagers. It is very important that children using salmeterol inhalation for asthma use it together with another long-term asthma control medication.

Do not give this medication to a child younger than 4 years old.

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Side Effects

What are the side effects of Serevent Diskus (Salmeterol Inhalation)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening asthma symptoms, or other breathing problems after using this medicine;
  • severe headache, blurred vision, pounding in your neck or ears;
  • chest pain, fast or irregular heartbeats;
  • tremors, nervousness;
  • high blood sugar–increased thirst, increased urination, dry mouth, fruity breath odor; or
  • low potassium level–leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Common side effects may include:

  • headache;
  • flu symptoms;
  • joint or muscle pain;
  • throat irritation, cough; or
  • stuffy or runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Serevent Diskus (Salmeterol Inhalation) if I’m pregnant or breastfeeding?

Risk cannot be ruled out
Based on FDA pregnancy categories

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.


What drugs and food should I avoid while taking Serevent Diskus (Salmeterol Inhalation)?

Do not exhale or blow into the Diskus device. Do not take the device apart or allow it to get wet.

Do not use a second form of salmeterol (such as Advair) or similar inhaled bronchodilator unless your doctor tells you to. This includes formoterol (Perforomist, Symbicort, Bevespi, Dulera), arformoterol (Brovana), indacaterol (Arcapta), olodaterol (Striverdi, Stiolto Respimat), or vilanterol (Anoro Ellipta, Breo Ellipta, Trelegy Ellipta).

Dosage Guidelines & Tips

How to take Serevent Diskus (Salmeterol Inhalation)?

Use Serevent Diskus (Salmeterol Inhalation) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Salmeterol may increase the risk of asthma-related death. Use the medicine exactly as directed.

Salmeterol is not a rescue medicine for asthma attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your asthma medications are not working as well.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

If you use salmeterol inhalation for asthma, you must use it together with an inhaled steroid medicine for long-term asthma control. Use all asthma medications as directed. Your dose needs may change due to surgery, illness, stress, or a recent asthma attack. Do not change your dose or dosing schedule without your doctor's advice.

Call your doctor if your symptoms do not improve after 7 days.

Do not stop using salmeterol inhalation without first talking to your doctor. Your asthma symptoms may get worse after you stop using the medication.

If you also use a steroid medication, you should not stop using it suddenly. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture, heat, and sunlight.

Do not try to clean or take apart the Diskus device. Throw it away 6 weeks after you have taken it out of the foil pouch, or if the dose indicator shows a zero, whichever comes first. Each Diskus device contains 60 doses.

What should I do if I missed a dose of Serevent Diskus (Salmeterol Inhalation)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

Get your prescription refilled before you run out of medicine completely.

Overdose Signs

What happens if I overdose on Serevent Diskus (Salmeterol Inhalation)?

If you think you or someone else may have overdosed on: Serevent Diskus (Salmeterol Inhalation),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Serevent Diskus (Salmeterol Inhalation), call 911



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