Relyvrio – Side Effects, Interactions, Uses, Dosage, Warnings

Sodium phenylbutyrate and taurursodiol is used to treat adults with amyotrophic lateral sclerosis (ALS).

Sodium phenylbutyrate and taurursodiol may also be used for purposes not listed in this medication guide.

uses

What is Relyvrio (Oral) used for?

  • Amyotrophic Lateral Sclerosis

warnings

What is the most important information I should know about Relyvrio (Oral)?

Tell your doctor if you have ever had:

  • liver or kidney disease;
  • pancreas problems;
  • intestinal problems; or
  • heart failure (including congestive heart failure) or high blood pressure.

Tell your doctor if you are pregnant or breastfeeding.

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Side Effects

What are the side effects of Relyvrio (Oral)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • new or worsening diarrhea; or
  • fluid retention–shortness of breath (even while lying down), swelling, rapid weight gain (especially in your face and midsection).

Common side effects may include:

  • diarrhea, stomach pain, nausea; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Relyvrio (Oral) if I’m pregnant or breastfeeding?

Tell your doctor if you are pregnant or breastfeeding.

Interactions

What drugs and food should I avoid while taking Relyvrio (Oral)?

Avoid taking antacids containing aluminum while you are using sodium phenylbutyrate and taurursodiol.

Dosage Guidelines & Tips

How to take Relyvrio (Oral)?

Use Relyvrio (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Sodium phenylbutyrate and taurursodiol should be taken before a snack or meal. Empty one packet of this medicine in a cup (8 ounces) with water (room temperature) and stir well.

Sodium phenylbutyrate and taurursodiol can be taken by mouth or through a feeding tube up to one hour after preparing it. Throw away any unused medicine after one hour.

Sodium phenylbutyrate and taurursodiol has a high salt (sodium) content. For people who are sensitive to salt intake (those with heart failure, high blood pressure, kidney problems, or other conditions related to sodium retention) the amount of salt ingested may need to be limited. Talk to your healthcare provider about the total amount of daily salt that is appropriate for you.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose of Relyvrio (Oral)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Relyvrio (Oral)?

If you think you or someone else may have overdosed on: Relyvrio (Oral),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Relyvrio (Oral), call 911

911

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