Recarbrio (Imipenem, Cilastatin, And Relebactam) – Side Effects, Interactions, Uses, Dosage, Warnings

Imipenem, cilastatin, and relebactam is a combination medicine that is used to treat complicated infections of the urinary tract (bladder and kidneys) or infections within the stomach area (abdomen).

Imipenem, cilastatin, and relebactam is also used to treat pneumonia (a lung infection) caused by being in a hospital or using a ventilator.

This medicine is for use in adults who have few or no other treatment options.

Imipenem, cilastatin, and relebactam may also be used for purposes not listed in this medication guide.


What is Recarbrio (Imipenem, Cilastatin, And Relebactam) used for?

  • Intraabdominal Infection
  • Pyelonephritis
  • Urinary Tract Infection
  • Tuberculosis – Urinary Tract
  • Infection – Bacterial/Fungal/Protozoal/Viral
  • Nosocomial Pneumonia


What is the most important information I should know about Recarbrio (Imipenem, Cilastatin, And Relebactam)?

You should not be treated with this medicine if you are allergic to imipenem, cilastatin, or relebactam.

Tell your doctor if you have ever had:

  • a seizure;
  • a stroke; or
  • an allergic reaction to penicillin or other antibiotic medicines.

Tell your doctor if you are pregnant or breastfeeding.

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Side Effects

What are the side effects of Recarbrio (Imipenem, Cilastatin, And Relebactam)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • tremors;
  • a seizure; or
  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose).

Common side effects may include:

  • increased blood pressure;
  • nausea, diarrhea, vomiting;
  • abnormal liver function tests;
  • fever;
  • headache; or
  • pain, bruising, swelling, or irritation where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Recarbrio (Imipenem, Cilastatin, And Relebactam) if I’m pregnant or breastfeeding?

Tell your doctor if you are pregnant or breastfeeding.


What drugs and food should I avoid while taking Recarbrio (Imipenem, Cilastatin, And Relebactam)?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Dosage Guidelines & Tips

How to take Recarbrio (Imipenem, Cilastatin, And Relebactam)?

Use Recarbrio (Imipenem, Cilastatin, And Relebactam) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

This medicine is given as an infusion into a vein. A healthcare provider will give you this injection.

You should receive this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.

Imipenem, cilastatin, and relebactam will not treat a viral infection such as the flu or a common cold.

What should I do if I missed a dose of Recarbrio (Imipenem, Cilastatin, And Relebactam)?

If you receive imipenem, cilastatin, and relebactam in a clinical setting, you are not likely to miss a dose.

Call your doctor for instructions if your infusions are given at home and you miss a dose.

Overdose Signs

What happens if I overdose on Recarbrio (Imipenem, Cilastatin, And Relebactam)?

If you think you or someone else may have overdosed on: Recarbrio (Imipenem, Cilastatin, And Relebactam),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Recarbrio (Imipenem, Cilastatin, And Relebactam), call 911


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