Potassium Phosphate – Side Effects, Interactions, Uses, Dosage, Warnings

Phosphorus is a naturally occurring substance that is important in every cell of the body. Phosphorous is contained in all body cells and is used for growth and repair of cells and tissues.

Potassium phosphate is used to treat or prevent hypophosphatemia (low blood levels of phosphorus). Potassium phosphate is sometimes added to intravenous (IV) fluids given to people who cannot eat or drink anything.

Potassium phosphate may also be used for purposes not listed in this medication guide.


What is Potassium Phosphate used for?

  • Hypophosphatemia


What is the most important information I should know about Potassium Phosphate?

You should not use potassium phosphate if you have:

  • high levels of potassium in your blood (hyperkalemia);
  • low levels of calcium in your blood (hypocalcemia); or
  • high levels of phosphorus in your blood (hyperphosphatemia).

Tell your doctor if you have ever had:

  • heart disease;
  • kidney disease; or
  • Addison's disease (an adrenal gland disorder).

Tell your doctor if you are pregnant or breastfeeding.

Do not give this medicine to a child younger than 4 years old without a doctor's advice.

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Side Effects

What are the side effects of Potassium Phosphate?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have any signs of electrolyte imbalance, such as:

  • confusion, severe weakness;
  • a light-headed feeling, like you might pass out;
  • nausea, chest pain, irregular heartbeats;
  • numbness or tingling in your arms or legs;
  • weakness or heavy feeling in your legs;
  • loss of movement in any part of your body; or
  • slow heart rate, weak pulse, fainting, slow breathing.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Potassium Phosphate if I’m pregnant or breastfeeding?

Risk cannot be ruled out
Based on FDA pregnancy categories

Tell your doctor if you are pregnant or breastfeeding.


What drugs and food should I avoid while taking Potassium Phosphate?

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid taking a vitamin or mineral supplement that contains calcium or vitamin D, unless your doctor tells you to.

Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb potassium phosphate.

Dosage Guidelines & Tips

How to take Potassium Phosphate?

Use Potassium Phosphate exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Potassium phosphate is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Potassium phosphate must be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light.

What should I do if I missed a dose of Potassium Phosphate?

Call your doctor for instructions if you miss a dose.

Overdose Signs

What happens if I overdose on Potassium Phosphate?

If you think you or someone else may have overdosed on: Potassium Phosphate,  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Potassium Phosphate, call 911


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