Potassium Citrate (Urocit-K) – Side Effects, Interactions, Uses, Dosage, Warnings

Potassium citrate is a mineral that is used to treat kidney stones.

Potassium citrate may also be used for purposes not listed in this medication guide.


What is Potassium Citrate (Urocit-K) used for?

  • Uric Acid Nephrolithiasis
  • Nephrolithiasis
  • Renal Tubular Acidosis


What is the most important information I should know about Potassium Citrate (Urocit-K)?

You should not use potassium citrate if you have:

  • high levels of potassium in your blood (hyperkalemia);
  • kidney failure;
  • a bladder or kidney infection;
  • untreated or uncontrolled diabetes;
  • an adrenal gland disorder;
  • a blockage in your intestines;
  • problems with your esophagus, stomach, or intestines that affect swallowing or digestion;
  • a peptic ulcer in your stomach;
  • wasting syndrome;
  • a large tissue injury (such as a severe burn);
  • if you are dehydrated or malnourished; or
  • if you take a "potassium-sparing" diuretic (amiloride, eplerenone, spironolactone, or triamterene).

Tell your doctor if you have ever had:

  • kidney problems other than kidney stones;
  • too much acid in your body (acidosis);
  • a stomach ulcer;
  • heart problems; or
  • chronic diarrhea (such as ulcerative colitis, Crohn's disease).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Potassium citrate is not approved for use by anyone younger than 18 years old.

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Side Effects

What are the side effects of Potassium Citrate (Urocit-K)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe vomiting or stomach pain;
  • high blood potassium–nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or
  • signs of stomach bleeding–bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • upset stomach, nausea, vomiting; or
  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Potassium Citrate (Urocit-K) if I’m pregnant or breastfeeding?

Risk cannot be ruled out
Based on FDA pregnancy categories

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.


What drugs and food should I avoid while taking Potassium Citrate (Urocit-K)?

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid strenuous exercise if you are not in proper condition for it.

Dosage Guidelines & Tips

How to take Potassium Citrate (Urocit-K)?

Use Potassium Citrate (Urocit-K) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take with a meal or bedtime snack, or within 30 minutes after a meal.

Swallow the tablet whole and do not crush, chew, break, or suck on it.

The tablet may irritate your mouth or throat. Tell your doctor if it feels like the tablet gets stuck in your throat when you swallow it.

You may need to follow a special diet while using potassium citrate. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.

You will need frequent urine and blood tests. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).

Limit your salt intake and drink plenty of fluids while taking potassium citrate.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What should I do if I missed a dose of Potassium Citrate (Urocit-K)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Potassium Citrate (Urocit-K)?

If you think you or someone else may have overdosed on: Potassium Citrate (Urocit-K),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Potassium Citrate (Urocit-K), call 911



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Color: yellow

Shape: round

Form: film coated

Imprint: MPC 600

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