Phytonadione (Vitamin K1) – Side Effects, Interactions, Uses, Dosage, Warnings

Phytonadione is a man-made form of vitamin K, which occurs naturally in the body.

Phytonadione is used to treat vitamin K deficiency, and to treat certain bleeding or blood-clotting problems caused by other medicines or medical conditions.

Phytonadione may also be used for purposes not listed in this medication guide.

uses

What is Phytonadione (Vitamin K1) used for?

  • Hypoprothrombinemia — Anticoagulant Induced
  • Hypoprothrombinemia — Not Associated with Anticoagulant Therapy
  • Hypoprothrombinemia — Prophylaxis
  • Vitamin K Deficiency

warnings

What is the most important information I should know about Phytonadione (Vitamin K1)?

You should not use phytonadione if you are allergic to it.

Tell your doctor if you have ever had liver disease.

Phytonadione injection may contain an ingredient that can cause serious side effects or death in very young or premature babies. Do not give this medicine to a child without medical advice.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

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Side Effects

What are the side effects of Phytonadione (Vitamin K1)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

A phytonadione injection may cause a serious allergic reaction. Tell your caregiver if you feel weak, tingly, light-headed, warm, itchy, or if you have a chest pain, trouble breathing, a cold sweat, or swelling in your face.

Call your doctor at once if you have:

  • unusual or unpleasant taste in your mouth;
  • a light-headed feeling, like you might pass out;
  • blue colored lips;
  • jaundice (yellowing of the skin or eyes);
  • trouble breathing;
  • weak but rapid pulse; or
  • skin redness, itching, or a hard lump where an injection was given.

Common side effects may include:

  • dizziness;
  • flushing (warmth, redness, or tingly feeling);
  • changes in your sense of taste;
  • sweating; or
  • pain or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Phytonadione (Vitamin K1) if I’m pregnant or breastfeeding?

C
Risk cannot be ruled out
Based on FDA pregnancy categories

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Interactions

What drugs and food should I avoid while taking Phytonadione (Vitamin K1)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to take Phytonadione (Vitamin K1)?

Use Phytonadione (Vitamin K1) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Never use phytonadione in larger amounts, or for longer than prescribed.

A phytonadione injection is given into a muscle, under the skin, or as an infusion into a vein. A healthcare provider will give the injection.

You may need frequent blood tests.

If you need surgery or dental work, tell the surgeon or dentist you currently use this medicine.

Store at room temperature away from moisture and heat. Protect from light. Keep the medicine in the original container and tightly closed when not in use.

What should I do if I missed a dose of Phytonadione (Vitamin K1)?

Call your doctor for instructions if you miss a dose of phytonadione.

Overdose Signs

What happens if I overdose on Phytonadione (Vitamin K1)?

If you think you or someone else may have overdosed on: Phytonadione (Vitamin K1),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Phytonadione (Vitamin K1), call 911

911

Images

MEPHYTON, VRX 405

Color: yellow

Shape: round

Imprint: MEPHYTON, VRX 405

MEPHYTON, MSD 43

Color: yellow

Shape: round

Imprint: MEPHYTON, MSD 43

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AA 05

Color: yellow

Shape: round

Imprint: AA 05

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