Pepcid AC (Famotidine Oral Injection) – Side Effects, Interactions, Uses, Dosage, Warnings

Famotidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.

Famotidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

The Zantac 360 brand of this medicine does not contain ranitidine, a medicine that was withdrawn from market in the United States.

Famotidine may also be used for purposes not listed in this medication guide.

uses

What is Pepcid AC (Famotidine Oral Injection) used for?

  • Duodenal Ulcer
  • Dyspepsia
  • Erosive Esophagitis
  • Gastric Ulcer
  • Gastroesophageal Reflux Disease
  • Zollinger-Ellison Syndrome
  • Peptic Ulcer
  • Pathological Hypersecretory Conditions
  • Peptic Ulcer with Hemorrhage
  • Peptic Ulcer with Hemorrhage and Perforation
  • Peptic Ulcer with Perforation
  • Peptic Ulcer with Hemorrhage and Obstruction
  • Peptic Ulcer with Perforation and Obstruction
  • Peptic Ulcer with Hemorrhage/Perforation/Obstruction
  • Peptic Ulcer with Obstruction

warnings

What is the most important information I should know about Pepcid AC (Famotidine Oral Injection)?

Heartburn can feel like a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder.

You should not use this medicine if you are allergic to famotidine or similar medicines such as ranitidine (Zantac), cimetidine (Tagamet), or nizatidine (Axid).

Ask a doctor or pharmacist if this medicine is safe to use if you have:

  • kidney disease;
  • liver disease;
  • cancer stomach; or
  • long QT syndrome (in you or a family member).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

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Side Effects

What are the side effects of Pepcid AC (Famotidine Oral Injection)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using famotidine and call your doctor at once if you have:

  • confusion, hallucinations, agitation, lack of energy;
  • a seizure;
  • fast or pounding heartbeats, sudden dizziness (like you might pass out); or
  • unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Some side effects may be more likely in older adults and in people who have severe kidney disease.

Common side effects may include:

  • headache;
  • dizziness; or
  • constipation or diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Pepcid AC (Famotidine Oral Injection) if I’m pregnant or breastfeeding?

B
No evidence of risk in humans
Based on FDA pregnancy categories

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Interactions

What drugs and food should I avoid while taking Pepcid AC (Famotidine Oral Injection)?

Drinking alcohol may increase the risk of damage to your stomach.

Avoid taking other stomach acid reducers unless your doctor has told you to. However, you may take an antacid (such as Maalox, Mylanta, Gaviscon, Milk of Magnesia, Rolaids, or Tums) with famotidine.

Dosage Guidelines & Tips

How to take Pepcid AC (Famotidine Oral Injection)?

Use Pepcid AC (Famotidine Oral Injection) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Use exactly as directed on the label, or as prescribed by your doctor.

Famotidine oral is taken by mouth.

Famotidine injection is given in a vein if you are unable to take the medicine by mouth.

You may take famotidine oral with or without food.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Most ulcers heal within 4 weeks of famotidine treatment, but it may take up to 8 weeks of using this medicine before your ulcer heals. Keep using the medication as directed.

Call your doctor if the condition you are treating with famotidine does not improve, or if it gets worse while using famotidine.

Your treatment may also include changes in diet or lifestyle habits. Follow all instructions of your doctor or dietitian.

Store at room temperature away from moisture, heat, and light. Do not allow the liquid medicine to freeze.

Throw away any unused famotidine liquid that is older than 30 days.

What should I do if I missed a dose of Pepcid AC (Famotidine Oral Injection)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Pepcid AC (Famotidine Oral Injection)?

If you think you or someone else may have overdosed on: Pepcid AC (Famotidine Oral Injection),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Pepcid AC (Famotidine Oral Injection), call 911

911

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