Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom) – Side Effects, Interactions, Uses, Dosage, Warnings

Acetaminophen is a pain reliever and fever reducer.

Magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). This medicine works by reducing substances in the body that cause pain, fever, and inflammation.

Pamabrom is a diuretic (water pill).

Acetaminophen, magnesium salicylate, and pamabrom is a combination medicine used to treat menstrual symptoms such as cramps, headache, backache, muscle aches, bloating, and fluid retention.

Acetaminophen, magnesium salicylate, and pamabrom may also be used for other purposes not listed in this medication guide.

warnings

What is the most important information I should know about Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom)?

You should not take this medication if you are allergic to acetaminophen (Tylenol), magnesium salicylate (Nuprin), pamabrom, aspirin or other NSAIDs.

Do not give this medication to a child or teenager with a fever, flu symptoms, or chicken pox. Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children.

Magnesium salicylate may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking acetaminophen, magnesium salicylate, and pamabrom, especially if you take this medicine for a long time, or:

  • if you are age 60 or older;
  • if you have a history of stomach ulcer or bleeding;
  • if you drink more than 3 alcoholic beverages per day;
  • if you take a blood thinner (warfarin, Coumadin), a steroid, or a diuretic ("water pill"); or
  • if you also take any other NSAID, such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

  • liver disease, cirrhosis, or history of alcoholism;
  • heartburn or other stomach problems;
  • high blood pressure, heart disease;
  • kidney disease;
  • gout;
  • diabetes; or
  • arthritis.

Magnesium salicylate may be harmful to an unborn baby if the mother takes the medication during the last 3 months of pregnancy. Do not take acetaminophen, magnesium salicylate, and pamabrom without telling your doctor if you are pregnant or plan to become pregnant during treatment.

This medicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Side Effects

What are the side effects of Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe stomach pain;
  • a light-headed feeling, like you might pass out;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • any redness or swelling; or
  • ringing in your ears or hearing problems.

Common side effects may include:

  • heartburn; or
  • upset stomach.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom) if I’m pregnant or breastfeeding?

Magnesium salicylate may be harmful to an unborn baby if the mother takes the medication during the last 3 months of pregnancy. Do not take acetaminophen, magnesium salicylate, and pamabrom without telling your doctor if you are pregnant or plan to become pregnant during treatment.

This medicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Interactions

What drugs and food should I avoid while taking Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom)?

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Dosage Guidelines & Tips

How to take Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom)?

Use Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Use exactly as directed on the label, or as prescribed by your doctor. Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Stop taking this medication and call your doctor if:

  • you have a fever lasting longer than 3 days;
  • you have pain lasting longer than 10 days; or
  • your symptoms get worse, or if you have any new symptoms.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using acetaminophen, magnesium salicylate, and pamabrom.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose of Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom)?

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Never take more than 8 tablets in one 24-hour period.

Overdose Signs

What happens if I overdose on Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom)?

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

If you think you or someone else may have overdosed on: Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Pamprin Cramp Formula (Apap Magnesium Salicylate Pamabrom), call 911

911

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