Norgesic Forte (Aspirin, Caffeine, And Orphenadrine) – Side Effects, Interactions, Uses, Dosage, Warnings

Aspirin, caffeine, and orphenadrine is a combination medicine that is used together with rest and physical therapy to treat painful muscular conditions.

Aspirin, caffeine, and orphenadrine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Norgesic Forte (Aspirin, Caffeine, And Orphenadrine)?

You should not use this medicine if you are allergic to aspirin, caffeine, or orphenadrine, or if you have:

  • glaucoma;
  • a blockage in your digestive tract (stomach or intestines);
  • a bladder obstruction or other urination problems;
  • an enlarged prostate;
  • myasthenia gravis; or
  • problems with the muscles in your esophagus (the tube that connects your mouth and stomach).

Tell your doctor if you have ever had:

  • a stomach ulcer; or
  • a bleeding or blood clotting disorder.

Tell your doctor if you are pregnant or breastfeeding.

Do not give this medicine to anyone with a fever, flu symptoms, or chickenpox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition.

Aspirin, caffeine, and orphenadrine is not approved for use by anyone younger than 12 years old.

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Side Effects

What are the side effects of Norgesic Forte (Aspirin, Caffeine, And Orphenadrine)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • confusion, anxiety;
  • fast or pounding heartbeats, fluttering in your chest;
  • tremors;
  • little or no urination;
  • eye pain, vision problems; or
  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • dry mouth;
  • blurred vision;
  • dizziness, drowsiness, weakness;
  • headache; or
  • nausea, vomiting, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Norgesic Forte (Aspirin, Caffeine, And Orphenadrine) if I’m pregnant or breastfeeding?

Tell your doctor if you are pregnant or breastfeeding.


What drugs and food should I avoid while taking Norgesic Forte (Aspirin, Caffeine, And Orphenadrine)?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain aspirin or other salicylates.

Dosage Guidelines & Tips

How to take Norgesic Forte (Aspirin, Caffeine, And Orphenadrine)?

Use Norgesic Forte (Aspirin, Caffeine, And Orphenadrine) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Call your doctor if your symptoms do not improve, or if they get worse.

If you use this medicine long-term, you may need frequent medical tests.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose of Norgesic Forte (Aspirin, Caffeine, And Orphenadrine)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Norgesic Forte (Aspirin, Caffeine, And Orphenadrine)?

If you think you or someone else may have overdosed on: Norgesic Forte (Aspirin, Caffeine, And Orphenadrine),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Norgesic Forte (Aspirin, Caffeine, And Orphenadrine), call 911




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