Nilutamide (Nilandron) – Side Effects, Interactions, Uses, Dosage, Warnings

Nilutamide is used to treat prostate cancer that has spread to other parts of the body.

Nilutamide is for use in men who have undergone surgical castration.

Nilutamide may also be used for purposes not listed in this medication guide.


What is Nilutamide (Nilandron) used for?

  • Prostate Cancer


What is the most important information I should know about Nilutamide (Nilandron)?

You should not use nilutamide if you are allergic to it, or if you have:

  • severe liver disease; or
  • severe breathing problems.

Tell your doctor if you have ever had:

  • liver disease; or
  • asthma or another lung disease.

Nilutamide is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.

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Side Effects

What are the side effects of Nilutamide (Nilandron)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • chest pain, wheezing, dry cough, fever;
  • new or worsening shortness of breath;
  • flu symptoms, pale skin, feeling tired; or
  • liver problems–nausea, vomiting, loss of appetite, right-sided upper stomach pain, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • hot flashes;
  • dizziness;
  • constipation;
  • nausea or vomiting, loss of appetite;
  • skin rash;
  • decreased libido, impotence; or
  • vision changes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Nilutamide (Nilandron) if I’m pregnant or breastfeeding?

Risk cannot be ruled out
Based on FDA pregnancy categories

Nilutamide is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.


What drugs and food should I avoid while taking Nilutamide (Nilandron)?

Nilutamide may cause a delay in your ability to see in the dark after you have been in a lighted area. Be careful when driving at night, when entering a tunnel, and in similar situations. Wearing tinted glasses may help lessen this effect.

Drinking alcohol with nilutamide may cause dizziness, flushing (warmth, redness, or tingly feeling), or other unpleasant symptoms.

Dosage Guidelines & Tips

How to take Nilutamide (Nilandron)?

Use Nilutamide (Nilandron) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Treatment with nilutamide should be started on the day of or on the day after surgical castration.

You may take nilutamide with or without food.

Do not stop taking this medication without first talking to your doctor.

Store at room temperature away from moisture and heat.

What should I do if I missed a dose of Nilutamide (Nilandron)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Nilutamide (Nilandron)?

If you think you or someone else may have overdosed on: Nilutamide (Nilandron),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Nilutamide (Nilandron), call 911



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