Netarsudil Ophthalmic (Rhopressa) – Side Effects, Interactions, Uses, Dosage, Warnings

Netarsudil lowers pressure inside the eye by increasing the amount of fluid that drains from the eye.

Netarsudil ophthalmic (for the eyes) is used to treat open-angle glaucoma or other causes of high pressure inside the eye.

Netarsudil ophthalmic may also be used for purposes not listed in this medication guide.


What is Netarsudil Ophthalmic (Rhopressa) used for?

  • Intraocular Hypertension
  • Glaucoma (Open Angle)


What is the most important information I should know about Netarsudil Ophthalmic (Rhopressa)?

You should not use netarsudil ophthalmic if you are allergic to it

Tell your doctor if you have ever had:

  • damage to the surface of your eye (also called the cornea).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Netarsudil ophthalmic is not approved for use by anyone younger than 18 years old.

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Side Effects

What are the side effects of Netarsudil Ophthalmic (Rhopressa)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe eye pain, redness, or irritation.

Common side effects may include:

  • eye redness;
  • blurred vision; or
  • pain after using the eyedrops.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Netarsudil Ophthalmic (Rhopressa) if I’m pregnant or breastfeeding?

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.


What drugs and food should I avoid while taking Netarsudil Ophthalmic (Rhopressa)?

Do not use other eye medications unless your doctor tells you to.

Dosage Guidelines & Tips

How to take Netarsudil Ophthalmic (Rhopressa)?

Use Netarsudil Ophthalmic (Rhopressa) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not use this medicine while wearing soft contact lenses. A preservative in the medicine could discolor the lenses. Use the medicine at least 15 minutes before inserting your contact lenses.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
  • Use only the number of drops your doctor has prescribed.
  • Wait at least 5 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Store an unopened bottle of eye drops in the refrigerator, do not freeze.

After you start using the eye drops, store them at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Throw away any unused eye drops after 6 weeks.

What should I do if I missed a dose of Netarsudil Ophthalmic (Rhopressa)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Netarsudil Ophthalmic (Rhopressa)?

If you think you or someone else may have overdosed on: Netarsudil Ophthalmic (Rhopressa),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Netarsudil Ophthalmic (Rhopressa), call 911


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