Neostigmine is used to reverse the effects of anesthesia medications used during surgery.
Neostigmine may also be used for purposes not listed in this medication guide.
uses
What is Neostigmine (Prostigmin) used for?
- Reversal of Neuromuscular Blockade
warnings
What is the most important information I should know about Neostigmine (Prostigmin)?
You should not be treated with neostigmine if you are allergic to it, or if you have:
- a bladder obstruction or other urination problems;
- a blockage in your digestive tract (stomach or intestines); or
- a serious disorder called peritonitis (inflammation of the membrane lining the organs inside your abdomen).
Tell your doctor if you have ever had:
- coronary artery disease (clogged arteries);
- a heart rhythm disorder; or
- myasthenia gravis.
Tell your doctor if you are pregnant or breastfeeding.
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Side Effects
What are the side effects of Neostigmine (Prostigmin)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers right away if you have muscle weakness as you wake up from surgery.
Common side effects may include:
- nausea, vomiting; or
- slow heartbeats.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Neostigmine (Prostigmin) if I’m pregnant or breastfeeding?
Tell your doctor if you are pregnant or breastfeeding.
Interactions
What drugs and food should I avoid while taking Neostigmine (Prostigmin)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dosage Guidelines & Tips
How to take Neostigmine (Prostigmin)?
Use Neostigmine (Prostigmin) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Neostigmine is given as an infusion into a vein. A healthcare provider will give you this injection.
Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.
Your doctor will also test your reflexes to make sure this medicine is effective in reversing the anesthesia.
Because is used when needed only for surgery, it does not have a daily dosing schedule.
Overdose Signs
What happens if I overdose on Neostigmine (Prostigmin)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
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