Mulpleta (Lusutrombopag) – Side Effects, Interactions, Uses, Dosage, Warnings

Lusutrombopag is a man-made form of a protein that increases production of platelets (blood-clotting cells) in your body. Lusutrombopag can lower the risk of bleeding by increasing platelets in your blood.

Lusutrombopag is used to treat thrombocytopenia (a lack of platelets in the blood) in adults with chronic liver disease who are scheduled to undergo a medical procedure.

Lusutrombopag is not a cure for thrombocytopenia and it will not make your platelet counts normal.

Lusutrombopag may also be used for purposes not listed in this medication guide.

uses

What is Mulpleta (Lusutrombopag) used for?

  • Aplastic Anemia
  • Thrombocytopenia
  • Thrombotic Thrombocytopenic Purpura
  • Hemolytic Uremic Syndrome
  • Bone Marrow Depression/Low Blood Counts
  • Pancytopenia

warnings

What is the most important information I should know about Mulpleta (Lusutrombopag)?

You should not use lusutrombopag if you are allergic to it.

Tell your doctor if you have ever had:

  • a blood clot; or
  • a bleeding or blood clotting disorder other than thrombocytopenia.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 28 days after your last dose.

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Side Effects

What are the side effects of Mulpleta (Lusutrombopag)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

You could develop a blood clot if your platelet count gets too high while you are taking lusutrombopag. Call your doctor or get emergency medical help if you have:

  • sudden numbness or weakness (especially on one side of the body);
  • problems with vision or speech;
  • swelling or redness in an arm or leg;
  • fever, chills;
  • stomach pain (upper right side), vomiting;
  • jaundice (yellowing of the skin or eyes); or
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Mulpleta (Lusutrombopag) if I’m pregnant or breastfeeding?

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 28 days after your last dose.

Interactions

What drugs and food should I avoid while taking Mulpleta (Lusutrombopag)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to take Mulpleta (Lusutrombopag)?

Use Mulpleta (Lusutrombopag) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Lusutrombopag is usually taken once daily for 7 days, beginning 8 to 14 days before your procedure.

You may take lusutrombopag with or without food.

Carefully follow your doctor's dosing instructions about the timing of this medication and your procedure.

Store at room temperature away from moisture and heat. Keep each tablet in the foil blister pack until you are ready to take a dose.

What should I do if I missed a dose of Mulpleta (Lusutrombopag)?

Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not use 2 doses in one day.

Overdose Signs

What happens if I overdose on Mulpleta (Lusutrombopag)?

If you think you or someone else may have overdosed on: Mulpleta (Lusutrombopag),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Mulpleta (Lusutrombopag), call 911

911

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Color: red

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Form: film coated

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