Mucinex (Guaifenesin) – Side Effects, Interactions, Uses, Dosage, Warnings

Guaifenesin is used to reduce chest congestion caused by the common cold, flu, or chronic bronchitis.

Guaifenesin helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

There are many brands and forms of guaifenesin available. Not all brands are listed on this leaflet.

Guaifenesin may also be used for purposes not listed in this medication guide.


What is Mucinex (Guaifenesin) used for?

  • Cough


What is the most important information I should know about Mucinex (Guaifenesin)?

You should not use guaifenesin if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

Ask a doctor before using this medicine if you are pregnant.

You should not breast-feed while using guaifenesin.

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Side Effects

What are the side effects of Mucinex (Guaifenesin)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

  • nausea; or
  • vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Mucinex (Guaifenesin) if I’m pregnant or breastfeeding?

Risk cannot be ruled out
Based on FDA pregnancy categories

Ask a doctor before using this medicine if you are pregnant.

You should not breast-feed while using guaifenesin.


What drugs and food should I avoid while taking Mucinex (Guaifenesin)?

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Dosage Guidelines & Tips

How to take Mucinex (Guaifenesin)?

Use Mucinex (Guaifenesin) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

To use guaifenesin granules, pour out the entire packet onto your tongue and swallow without chewing.

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using guaifenesin.

Store at room temperature away from moisture and heat. Do not freeze.

What should I do if I missed a dose of Mucinex (Guaifenesin)?

Since cough or cold medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Mucinex (Guaifenesin)?

If you think you or someone else may have overdosed on: Mucinex (Guaifenesin),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Mucinex (Guaifenesin), call 911



600, Mucinex

Color: blue/white

Shape: oval

Imprint: 600, Mucinex


Color: green

Shape: oblong

Imprint: MEDEVA, 012


Color: white

Shape: oblong

Imprint: LIQU IBID

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