Mitapivat – Side Effects, Interactions, Uses, Dosage, Warnings

Mitapivat is used to treat low red blood cell counts caused by hemolytic anemia (early breakdown of red blood cells) in adults with pyruvate kinase deficiency.

Mitapivat may also be used for purposes not listed in this medication guide.

uses

What is Mitapivat (Oral) used for?

  • Anemia
  • Hemolytic Anemia
  • G-6-PD Deficiency
  • Thalassemia
  • Sickle Cell Anemia
  • Thrombotic Thrombocytopenic Purpura
  • Hemoglobinopathy
  • Hemolytic Uremic Syndrome
  • Autoimmune Hemolytic Anemia
  • Bone Marrow Depression/Low Blood Counts

warnings

What is the most important information I should know about Mitapivat (Oral)?

Tell your doctor if you have ever had:

  • liver disease.

Tell your doctor if you are pregnant or breastfeeding.

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Side Effects

What are the side effects of Mitapivat (Oral)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • jaundice (yellowing of the skin or eyes);
  • dark urine;
  • dizziness;
  • confusion;
  • tiredness; or
  • shortness of breath.

Common side effects may include:

  • flushing (sudden warmth, redness, or tingly feeling);
  • breast swelling and tenderness;
  • changes in sexual function;
  • irregular heart rhythm;
  • abnormal blood tests; or
  • back or joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Mitapivat (Oral) if I’m pregnant or breastfeeding?

Tell your doctor if you are pregnant or breastfeeding.

Interactions

What drugs and food should I avoid while taking Mitapivat (Oral)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dosage Guidelines & Tips

How to take Mitapivat (Oral)?

Use Mitapivat (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take mitapivat with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Do not share this medicine with another person, even if they have the same symptoms you have.

Do not change your dose or stop using mitapivat without talking to your doctor. Your doctor will give you instructions for stopping mitapivat.

Store this medicine in the original container at room temperature.

What should I do if I missed a dose of Mitapivat (Oral)?

Use the medicine as soon as you can, but skip the missed dose if you are more than 4 hours late for the dose. Do not use two doses at one time.

Overdose Signs

What happens if I overdose on Mitapivat (Oral)?

If you think you or someone else may have overdosed on: Mitapivat (Oral),  call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn't breathing after taking Mitapivat (Oral), call 911

911

Images

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M50

Color: blue

Shape: oblong

Form: film coated

Imprint: M50

No image available

M20

Color: blue

Shape: round

Form: film coated

Imprint: M20

No image available

M5

Color: blue

Shape: round

Form: film coated

Imprint: M5

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