Lofexidine works by blocking the release of norepinephrine, a hormone similar to adrenaline that contributes to opioid withdrawal symptoms.
Lofexidine is used to reduce opioid withdrawal symptoms after you stop taking an opioid suddenly.
Lofexidine will not treat opioid addiction.
Lofexidine may also be used for purposes not listed in this medication guide.
uses
What is Lucemyra (Lofexidine) used for?
- Opiate Withdrawal
warnings
What is the most important information I should know about Lucemyra (Lofexidine)?
You should not use lofexidine if you are allergic to it.
Tell your doctor if you have ever had:
- slow heartbeats;
- low blood pressure;
- heart problems;
- a heart attack or stroke;
- an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
- long QT syndrome (in you or a family member);
- kidney disease; or
- liver disease.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Lofexidine is not approved for use by anyone younger than 18 years old.
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Side Effects
What are the side effects of Lucemyra (Lofexidine)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- slow heartbeats;
- severe dizziness or drowsiness; or
- a light-headed feeling, like you might pass out.
Common side effects may include:
- low blood pressure;
- dizziness (especially when standing up);
- drowsiness; or
- dry mouth.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy & Breastfeeding
Can I take Lucemyra (Lofexidine) if I’m pregnant or breastfeeding?
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Interactions
What drugs and food should I avoid while taking Lucemyra (Lofexidine)?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Avoid becoming overheated or dehydrated, or you could have very low blood pressure.
Avoid drinking alcohol.
Dosage Guidelines & Tips
How to take Lucemyra (Lofexidine)?
Use Lucemyra (Lofexidine) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take lofexidine with or without food.
You may need to take lofexidine for up to 14 days. Your doctor will change your dose or stop this treatment based on your opioid withdrawal symptoms. Follow all dosing instructions very carefully.
Lofexidine may not completely prevent all symptoms of opioid withdrawal, which may include yawning, pounding heartbeats, watery eyes, feeling cold, stomach pain, feeling sick, body aches, muscle tightness, or trouble sleeping.
You may need additional forms of counseling, support, and/or monitoring as you go through opioid withdrawal.
Lofexidine can cause serious side effects on your heart or blood vessels. Call your doctor at once if you have slow heartbeats, severe dizziness, or a light-headed feeling (like you might pass out). If you have these side effects, do not take your next lofexidine dose until you talk with your doctor.
You should not stop using lofexidine suddenly, or you could have a rapid increase in blood pressure and unpleasant symptoms. Follow your doctor's instructions about tapering your dose.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture- absorbing preservative.
If you start using opioid medication after a long period of not using it, you will be more sensitive to opioid effects. This could increase your risk of overdose and death.
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
Overdose Signs
What happens if I overdose on Lucemyra (Lofexidine)?
(800) 222-1222
911
Images
LFX, 18
Color: peach
Shape: round
Form: film coated
Imprint: LFX, 18