Lonafarnib (Zokinvy) – Side Effects, Interactions, Uses, Dosage, Warnings

Side Effects

What are the side effects of Lonafarnib (Zokinvy)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• new or worsening vision problems (such as decreased night vision);
• severe ongoing nausea, vomiting, diarrhea;
• loss of appetite that causes weight loss;
• high blood pressure–severe headache, blurred vision, shortness of breath, nosebleeds, pounding in your neck or ears;
• kidney problems–little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
• high potassium level–nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;
• low potassium level–leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;
• low sodium level –headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady;
• low calcium level–muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes); or
• signs of infection–fever, chills, cough, rash, swelling, diarrhea, pain or burning when you urinate.

Common side effects may include:

• an electrolyte imbalance (such as low levels of potassium, sodium, or calcium in your blood);
• infection;
• increased blood pressure;
• stomach pain, nausea, vomiting, diarrhea;
• decreased appetite, weight loss;
• headache;
• feeling tired;
• muscle or joint pain;
• cold symptoms such as stuffy nose, sneezing, sore throat, cough; or
• abnormal lab tests;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.